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Kazutoyo Terada Selected Research

Angiopoietin-Like Protein 2

1/2021Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
12/2019Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.
1/2019Angiopoietin-Like Protein 2 Promotes the Progression of Diabetic Kidney Disease.
1/2018Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction.
1/2017ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis.
2/2016Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
1/2016Macrophage-Derived Angiopoietin-Like Protein 2 Exacerbates Brain Damage by Accelerating Acute Inflammation after Ischemia-Reperfusion.
1/2016Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.
3/2015ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.
12/2014Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.
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Kazutoyo Terada Research Topics

Disease

8Neoplasms (Cancer)
01/2021 - 10/2003
6Inflammation (Inflammations)
01/2018 - 01/2013
3Neoplasm Metastasis (Metastasis)
01/2018 - 01/2014
2Muscular Atrophy (Muscle Atrophy)
01/2019 - 01/2018
2Osteosarcoma (Osteogenic Sarcoma)
01/2018 - 01/2014
2Fibrosis (Cirrhosis)
10/2016 - 02/2016
2Atherosclerosis
01/2016 - 04/2014
1Kidney Neoplasms (Kidney Cancer)
06/2019
1Renal Cell Carcinoma (Grawitz Tumor)
06/2019
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2019
1Sarcopenia
01/2018
1Heart Failure
01/2018
1Hypoxia (Hypoxemia)
01/2018
1Psoriasis (Pustulosis Palmaris et Plantaris)
10/2016
1Interstitial Lung Diseases (Interstitial Lung Disease)
10/2016
1Chronic Renal Insufficiency
02/2016
1Rheumatoid Arthritis
01/2016
1Ischemia
01/2016
1Encephalitis (Encephalitis, Rasmussen)
01/2016
1Bacterial Infections (Bacterial Infection)
01/2016
1Obesity
01/2016
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2016
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2016
1Breast Neoplasms (Breast Cancer)
03/2015
1Carcinogenesis
12/2014
1Colorectal Neoplasms (Colorectal Cancer)
12/2014
1Atherosclerotic Plaque (Atheroma)
04/2014

Drug/Important Bio-Agent (IBA)

13Angiopoietin-Like Protein 2IBA
01/2021 - 01/2013
6Proteins (Proteins, Gene)FDA Link
06/2019 - 02/2012
2CytokinesIBA
01/2016 - 01/2016
1CarcinogensIBA
01/2021
1Biomarkers (Surrogate Marker)IBA
06/2019
1MicroRNAs (MicroRNA)IBA
06/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2018
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2018
1Monoclonal AntibodiesIBA
01/2018
1Interleukin-6 (Interleukin 6)IBA
01/2018
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018
1Bleomycin (Blenoxane)FDA LinkGeneric
10/2016
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2016
1Angiopoietin-like ProteinsIBA
01/2016
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016
1InterleukinsIBA
01/2016
1Syk KinaseIBA
12/2014
1Antineoplastic Agents (Antineoplastics)IBA
12/2014
1Phosphatidylinositols (Phosphatidylinositol)IBA
12/2014
1ApolipoproteinsIBA
04/2014
1Apolipoproteins E (ApoE)IBA
04/2014
1EnzymesIBA
01/2014
1p38 Mitogen-Activated Protein KinasesIBA
01/2014
1Peptide Hydrolases (Proteases)FDA Link
01/2014
1Matrix Metalloproteinases (MMPs)IBA
01/2014
1IntegrinsIBA
01/2014
1tipifarnib (R115777)IBA
10/2003
1Biological ProductsIBA
10/2003
1Farnesyltranstransferase (Farnesyltransferase)IBA
10/2003
1GemcitabineFDA Link
10/2003

Therapy/Procedure

3Therapeutics
01/2018 - 12/2014
2Denervation
01/2019 - 01/2018
1Resistance Training
01/2018
1Drug Therapy (Chemotherapy)
12/2014
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2014